Line C’s route was conceived to link the city’s eastern quadrant with its northwest quadrant. Starting from the Pantano terminus in the Municipality of Montecompatri, the line stretches for about 25.6 Km, approximately 9 of which on the surface and 16.5 underground, traversing such historic city neighbourhoods as Centocelle, Alessandrino, Pigneto, Appio, and the historic centre before reaching the Prati neighbourhood in the vicinity of Piazzale Clodio. Its completion will make a truly integrated public transport network possible. The Line C design in fact plans 4 interchanges:
- Line FR 1 at Pigneto;
- Line A at San Giovanni;
- Line B at Colosseo/Fori Imperiali;
- Line A at Ottaviano.
Line C is Rome’s first major driverless public transport infrastructure – that is to say that it is remotely driven and controlled by a fully automated system.